Egg Consumption and Cancer Risks

 

The Link Between Egg Consumption and Cancer Risk: What You Need to Know

Written by Clinical Nutritionist Keith Bishop
www.PrevailOverCancer.com

Are you among those eager to delve into the relationship between egg consumption and cancer risks? I certainly am! This topic has been the focus of my research for several days, driven by the high cancer risks my wife and I face. I want you to understand that I’m not just a researcher but also a consumer. I live in the countryside, had free-range chickens, and have enjoyed eggs for most of my life.

Eggs, a dietary staple worldwide, are valued for their protein, vitamins, fat content, and versatility. They are often thought to be the perfect food. While clinical health studies have presented conflicting results on cancer risks, it's important to note that some studies indicate the potential benefits of egg consumption. However, the majority of research suggests that frequent egg consumption may be linked to an increased risk of several types of cancer. The key, it seems, is moderation.

High egg consumption is associated with various types of cancer, including bladder cancer, breast cancer, ovarian cancer, prostate cancer, colon cancer, and colorectal cancer. You need to understand these risks, as how we cook eggs and certain compounds found in eggs, such as choline and IGF-1, may also increase these risks. This understanding will help you make informed decisions about including eggs in your diet, keeping you engaged and interested in your health.

The Connection Between Eggs and Cancer Risk

Eggs are a staple in many diets worldwide, prized for their protein content and versatility. Clinical health studies have revealed contradictory cancer risks. A few studies suggest no concern, many studies show potential problems, and some show potential benefits. Overall, research indicates that frequent egg consumption may be linked to an increased risk of several types of cancer. Moderation appears to be the key, as an increased risk of cancer is associated with a higher intake of eggs.

Recent studies have shed light on the potential risks associated with high egg consumption and its association with various types of cancer, including bladder cancer, breast cancer, ovarian cancer, prostate cancer, colon cancer, and colorectal cancer. You need to understand these risks, as how we cook eggs and certain compounds found in eggs, such as choline and IGF-1, may also increase these risks. This understanding will help you make informed decisions about including eggs in your diet, keeping you engaged and interested in your health.

Bladder Cancer: Fried eggs are associated with a significantly increased risk of bladder cancer, while boiled eggs are associated with a very modest risk.

Breast Cancer: I did find one dietary from China that found six eggs weekly reduced the risk of breast cancer, while two or fewer per week was associated with an increased risk of breast cancer. Most studies have found a correlation between high egg intake and an elevated risk of breast cancer. The suggested mechanism involves the dietary cholesterol in eggs, which may affect estrogen levels and, consequently, breast cancer risk.

Colorectal Cancer & Colon Cancer: The more eggs consumed, the more association with the development of gastrointestinal cancer, including colorectal cancer. Consuming eggs is associated with a higher risk of colon polyps. Consuming eggs more than 2-3 times a week may be associated with 3.67 times more likely to develop colon cancer. Consuming eggs, especially when cooked at high temperatures, may also be linked to a higher risk of colon and colorectal cancers.

Ovarian Cancer: The choline found in eggs has been under scrutiny for its potential role in increasing the risk of ovarian cancer. Choline is essential for health, but it may have adverse effects in excess.

Prostate Cancer: Research indicates a possible association between egg consumption and an increased risk of prostate cancer, particularly aggressive forms. In one dietary analysis, men who ate more than three eggs a week had a significant 14% increased risk of advanced and fatal prostate cancers. Another study found that by consuming 2.5 eggs per week, men increased their risk for a deadly form of prostate cancer by 81 percent, compared with men who consumed less than half an egg per week. A study published in 2022 found each additional egg per day was associated with a 13% higher risk of cancer mortality. This may be related to the intake of choline and the increase in IGF-1 (Insulin-like Growth Factor-1), which can promote cancer growth.

Personal Note: I've noticed my PSA increases when I consume eggs each day for breakfast. 

The Role of Cooking Eggs and Temperature

The temperature at which eggs are cooked can influence the formation of harmful compounds, potentially increasing cancer risk. High-temperature cooking methods, such as frying or boiling, may lead to the formation of these compounds, suggesting that lower-temperature cooking methods may be a healthier alternative. Fried eggs are associated with a significantly increased risk of bladder cancer, while boiled eggs are associated with a very modest risk.

Concerns with Choline and IGF-1

Eggs are a significant source of choline, an essential nutrient for brain health and other bodily functions. However, in high amounts, choline can be converted into a compound that may increase the risk of cancer. Similarly, eggs can raise levels of IGF-1, a growth factor that, while necessary for growth and development, has been linked to cancer progression when present in high levels in the body.

Making Informed Cancer Food Choices

Understanding the potential risks associated with egg consumption, particularly cancer, is essential for making informed dietary choices. While eggs can be part of a healthy diet, moderation is key. In summary, consuming less than six eggs weekly is associated with a reduced risk of cancer and death from cancer.

Consider varying your protein sources and incorporating a wide range of fruits, vegetables, legumes, nuts, seeds, and a potentially few whole grains to support overall health and reduce cancer risk. Additionally, opting for lower-temperature cooking methods and being mindful of the overall balance of your diet can help mitigate some of the risks associated with egg consumption.

For those navigating the complexities of health and wellness, especially cancer prevention and survivorship, staying informed about the latest research and dietary recommendations is crucial. As always, consult a healthcare provider or a nutrition expert to tailor nutritional choices to your specific health needs and goals.

Remember, your diet is a powerful tool in your health journey, and making small, informed changes can significantly impact your overall well-being.

Reference Sources Include

Mousavi SM, Zargarzadeh N, Rigi S, et al. Egg Consumption and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-analysis of Prospective Studies. Adv Nutr. 2022;13(5):1762-1773. doi:10.1093/advances/nmac040 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526855/

Keum, N., D. H. Lee, N. Marchand, H. Oh, H. Liu, D. Aune, D. C. Greenwood, and E. L. Giovannucci. 2015. “Egg Intake and Cancers of the Breast, Ovary and Prostate: A Dose–response Meta-Analysis of Prospective Observational Studies.” British Journal of Nutrition 114 (7): 1099– 1107. https://doi.org/10.1017/s0007114515002135.

Manije Darooghegi Mofrad, Sina Naghshi, Keyhan Lotfi, Joseph Beyene, Elina Hypponen, Aliyar Pirouzi, and Omid Sadeghi. Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. Front. Nutr., 26 May 2022. Sec. Nutritional Epidemiology. https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.878979/full#h1

Li F, Zhou Y, Hu RT, et al. Egg consumption and risk of bladder cancer: a meta-analysis. Nutr Cancer. 2013;65(4):538-546. doi:10.1080/01635581.2013.770041 https://www.tandfonline.com/doi/full/10.1080/01635581.2013.770041

Tse, G., Eslick, G.D. Egg consumption and risk of GI neoplasms: dose–response meta-analysis and systematic review. Eur J Nutr 53, 1581–1590 (2014). https://doi.org/10.1007/s00394-014-0664-5

Wilson KM, Mucci LA, Drake BF, et al. Meat, Fish, Poultry, and Egg Intake at Diagnosis and Risk of Prostate Cancer Progression. Cancer Prev Res (Phila). 2016;9(12):933-941. doi:10.1158/1940-6207.CAPR-16-0070 https://aacrjournals.org/cancerpreventionresearch/article/9/12/933/50487/Meat-Fish-Poultry-and-Egg-Intake-at-Diagnosis-and

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Johansson M, Van Guelpen B, Vollset SE, Hultdin J, Bergh A, Key T, et al One-carbon metabolism and prostate cancer risk: prospective investigation of seven circulating B vitamins and metabolites. Cancer Epidemiol Biomarkers Prev 2009;18:1538–43. https://aacrjournals.org/cebp/article/18/5/1538/164659/One-Carbon-Metabolism-and-Prostate-Cancer-Risk

Steinmetz, K A; Potter, J D. Egg consumption and cancer of the colon and rectum. European Journal of Cancer Prevention 3(3):p 237-246, May 1994. https://journals.lww.com/eurjcancerprev/Abstract/1994/03030/Egg_consumption_and_cancer_of_the_colon_and_rectum.2.aspx

Richman EL, Kenfield SA, Stampfer MJ, et al. Choline intake and risk of lethal prostate cancer: incidence and survival. Am J Clin Nutr. 2012;96(4):855-863. doi:10.3945/ajcn.112.039784  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441112/

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Shen J, Li Y, Xu M, et al. Association of egg consumption with colorectal polyp prevalence: findings from the Lanxi Pre-Colorectal Cancer Cohort (LP3C) in China. Food Funct. 2023;14(6):2597-2606. Published 2023 Mar 20. doi:10.1039/d2fo03061f https://pubs.rsc.org/en/content/articlelanding/2023/fo/d2fo03061f

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