How the Sunshine Hormone Reduces Cancer Risk, Activates Your Cancer-Fighting Immune System, and What Your Blood Test Number Actually Means

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist, and Founder of Prevail Over Cancer and the Prevail Protocol.

⚕️ Educational Disclaimer

This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Vitamin D3 supplementation should always be discussed with your oncologist or integrative medicine provider, particularly if you are currently undergoing cancer treatment. Individual needs vary significantly. This content does not reflect the official position of the FDA, NCI, or any medical governing body.

Introduction: The Overlooked Hormone That Fights Cancer

Vitamin D3 — widely known as the "sunshine vitamin" — is one of the most extensively researched nutrients in cancer science today. Yet despite decades of compelling evidence, vitamin D3 defici...

A Peer-Reviewed Clinical Guide for Clinicians and Patients on Astaxanthin's Anticancer Mechanisms, Natural Sources, and Therapeutic Integration

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Integrative Cancer Educator, Retired Pharmacist, and Founder of Prevail Over Cancer and the Prevail Protocol.

Key Takeaways

• Astaxanthin (ASX) is a keto-carotenoid derived primarily from the microalga Haematococcus pluvialis and marine seafood, with antioxidant potency up to 100 times greater than vitamin E.
• Peer-reviewed research documents nine distinct anticancer mechanisms, including NF-κB suppression, Nrf2 activation, apoptosis induction, STAT3 inhibition, and anti-metastatic activity.
• Preclinical evidence spans breast, colon, liver, prostate, lung, leukemia, melanoma, gastric, and oral cancers.
• Emerging 2024–2025 research identifies new mechanisms, including modulation of the gut microbiota and targeting of the USP39/β-catenin pathway in hepatocellular ca
...

Researched and Written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist, and founder of Prevail Over Cancer and the Prevail Protocol

Why Should We Consider Short-Term Fasting During Chemotherapy Treatments?

Short-term fasting (STF) has shown promise in enhancing the efficacy of cancer treatments while protecting healthy cells from toxicity. Studies suggest that STF can slow tumor growth and improve the quality of life for cancer patients.

Short-term fasting (STF) has shown promising effects on cancer cells in the human body, according to several medical journal references. Here are some key findings:

1. Differential Stress Resistance (DSR): STF protects healthy cells from the toxic effects of chemotherapy while making cancer cells more vulnerable to treatment. This is because healthy cells can enter a maintenance and repair mode during fasting, while cancer cells, which rely heavily on glucose, struggle to adapt.
2. Enhanced Chemotherapy Efficacy: Preclinica
...

Understanding fungal DNA in cancer tumors, terrain imbalances, antifungal foods, and how metabolism shapes fungal behavior in the body.

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist, and Founder of Prevail Over Cancer and the Prevail Protocol. 

 Why Fungi Are Being Found in Human Tumors

Large sequencing studies have confirmed that low-abundance fungal DNA and fungal cells appear across multiple cancer types — including breast, lung, GI, melanoma, and gynecologic tumors. These findings do not indicate infection and do not establish fungi as carcinogens. Instead, they highlight fungi as ecological participants within the tumor microenvironment.

• The Cell pan‑cancer analysis identified cancer‑type-specific fungal signatures, often co-occurring with distinct bacterial communities and immune phenotypes.
• A second Cell study confirmed the presence of fungi in GI and lung tumors and demonstrated associations with immune infiltration...

A science-based look at how GLP-1 hormones influence metabolism, inflammation, and cancer-related pathways—plus natural strategies to support your body’s own GLP‑1 production.

Written and researched by Keith Bishop, Clinical Nutritionist, Cancer Coach, Integrative Cancer Educator, Retired pharmacist, and founder of Prevail Over Cancer™ and the Prevail Protocol™.

GLP‑1, Metabolism, and Cancer

GLP-1 has become one of the most widely discussed hormones in modern health, largely because of medications like semaglutide and tirzepatide. But long before these drugs existed, your body was already producing GLP-1 naturally.

And here’s the part most people don’t realize:

GLP‑1 doesn’t just influence appetite and blood sugar—it also affects inflammation, insulin signaling, immune function, and cancer-related metabolic pathways.

This blog breaks down:

• What GLP-1 does
• How to support it naturally
• What current research says about GLP‑1 and cancer
• Which cancers show potential benefit
• Whic
...

Processed food’s carbohydrates and fats increase your body’s production of cancerous Methylglyoxal.

Written by Keith Bishop, Clinical Nutritionist, Cancer Coach, and Retired Pharmacist

Processed foods are a staple in many diets, but have hidden dangers that could significantly impact your health. One such danger is methylglyoxal, a by-product of glucose metabolism. Recent research has uncovered a concerning link between methylglyoxal and an increased risk of cancer.

What is Methylglyoxal?

Methylglyoxal is produced when our cells break down glucose to release energy. While it's a natural by-product, excessive levels can be harmful. Diets high in processed foods, often rich in carbohydrates and unhealthy fats, can increase methylglyoxal production.

The Cancer Connection Studies have shown that high levels of methylglyoxal can inhibit genes that protect against cancer, such as BRCA2. This inhibition can damage DNA and increase the likelihood of cancer development.

The typical Weste...

Understanding what Modified Citrus Pectin (MCP) Pectasol-C® is, how it interacts with galectin‑3 and cancer, what the research shows, and what patients should know about safety, interactions, and integrative oncology considerations.

What Is Modified Citrus Pectin?

Modified citrus pectin (MCP), Pectasol-C, is a form of pectin derived from the peel and pulp of citrus fruits. Unlike regular pectin—which is too large to be absorbed—MCP is processed into smaller, low‑molecular‑weight fragments that the body can absorb more easily.

MCP is rich in galactoside residues, which give it a unique ability to bind to certain proteins involved in cancer biology, especially galectin‑3.

Pectasol-C® is a brand of MCP. 

How MCP May Influence Cancer Biology

Much of MCP’s anticancer interest comes from its ability to bind and block galectin‑3, a protein involved in:

• Tumor growth[i]
• cell adhesion
• metastasis[ii]
• angiogenesis
• immune evasion
• apoptosis resistance

Galectin‑3 is overexpressed ...

How pumpkin seeds support anticancer nutrition, key nutrients, research findings, and practical guidance. 

Research and written by Keith Bishop, Cancer Coach, Clinical Nutritionist, Retired Pharmacist, and Founder of Prevail Over Cancer™ and the Prevail Protocol™

Pumpkin seeds—often treated as a simple snack—are quietly becoming one of the most compelling foods in anticancer nutrition. Rich in bioactive compounds, antioxidants, lignans, and unique proteins, these seeds have demonstrated promising effects in laboratory studies and population research. Below is a comprehensive, evidence-based look at what we know so far.

Anticancer Actions of Pumpkin Seeds

Pumpkin Seed Apoptosis-Inducing Activity

Pumpkin seed protein fractions have been shown to induce apoptosis (programmed cell death) in cancer cells, including liver (HepG2) and triple-negative breast cancer (MDA-MB-231) cell lines.[i]

Antioxidant & Anti-Inflammatory Effects

Pumpkin seeds contain phenolic compounds, tocopherol...

The Anticancer Actions of IV Vitamin C: Mechanisms, Dosing, Safety Labs, and Integration with Oncology Care

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, and Founder of Prevail Over Cancer™, and the Prevail Protocol™

High-dose intravenous vitamin C (IVC) has reemerged as a promising adjunctive therapy in integrative oncology. Modern research highlights its unique pharmacology, potential anticancer mechanisms, and its ability to support patients undergoing chemotherapy, radiation, and immunotherapy. This guide breaks down the science, dosing considerations, safety labs, and clinical integration—supported by peer-reviewed medical literature.

What Makes IV Vitamin C Different From Oral Vitamin C?

Oral vitamin C absorption is tightly limited by intestinal transporters, which cap blood levels even at high doses. In contrast, IV administration bypasses intestinal absorption and produces blood concentrations 100–500× higher than those required for a...

Does Coffee Protect Against Cancer? A Deep Dive into the Studies and Controversies

Researched and Written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist, and Founder of Prevail Over Cancer

Coffee appears to have some significant cancer-fighting benefits.👏👏👏 According to 📚medical research, coffee is associated with a reduced risk of cancer. There’s even a study that found higher coffee consumption is associated with reduced mortality from colorectal cancer.

Several compounds found in coffee possess antioxidant, anti-inflammatory, and insulin-sensitizing effects, which may contribute to anticancer activity.

In most studies, 3 ☕️☕️☕️ or more cups daily provide better protection than 1 cup daily. If you are sensitive to caffeine, you may have to limit your consumption, dilute the coffee, drink early in the day, or switch to naturally decaffeinated. Naturally decaffeinated coffee will not have as many beneficial anti-cancer ingredients. 

The strongest anticanc...