Researched and written by Keith Bishop, Cancer Coach, Clinical Nutritionist, Retired Pharmacist

D-mannose, a simple sugar, has been studied for its potential anti-cancer actions. Below, we explore its mechanisms, effects on cancer treatments, and considerations for its use based on scientific research. Mannose cancer research is in the early stages and is limited to laboratory cancer cell studies, a few animal studies, and even fewer human studies.

The Warburg Cancer Effect and D-Mannose

The Warburg effect is a phenomenon in which cancer cells rely heavily on glycolysis (glucose) for energy production, even in the presence of oxygen. Research indicates that D-mannose can disrupt glycolysis, affecting the Warburg effect and reducing cancer cell proliferation. A study published in Nature Nature link shows how D-mannose interferes with glucose metabolism, impairing tumor growth.

D-Mannose's Impact on Glucose Metabolism in Cancer

D-mannose alters glucose metabolism by inhibiting path...