By Keith Bishop | Clinical Nutritionist, Cancer Coach, Retired Pharmacist | Prevail Over Cancer
If your liver has already done the hard work of neutralizing a toxin or excess hormone — but your gut is quietly undoing all of that work before it can leave your body — you have an enzyme problem.
That enzyme is called beta-glucuronidase. And one of the most-researched natural compounds for addressing it is calcium D-glucarate.
In this post, we'll break down exactly what calcium D-glucarate is, how it works at the biochemical level, what the research shows across multiple cancer types, and where it fits inside a comprehensive integrative oncology protocol.
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Calcium D-glucarate is the calcium salt of D-glucaric acid — a naturally occurring compound produced in small amounts by the human body and found abundantly in a variety of plant foods. The calcium is there for stability in supplement form. The active ingredient is the glucarate portion.
Glucaric a...
If you add only one food to your anticancer nutrition plan, the research points strongly to one answer: broccoli sprouts. These tiny, unassuming seedlings — available at most grocery stores or easy to grow at home — contain concentrations of the most well-studied anticancer phytochemical on Earth.
That compound is sulforaphane (SFN) — an isothiocyanate derived from cruciferous vegetables that has now been investigated in over 3,000 published studies. And unlike many "superfoods" hyped on social media, sulforaphane's mechanisms are deeply understood at the molecular level, spanning cancer prevention, cancer stem cell targeting, chemotherapy enhancement, radiation sensitization, and immunotherapy support.
This research blog compiles everything the current science tells us about broccoli sprouts and cancer — including how sulforaphane works, how to maximize the amount you produce and absorb, and how it interacts with ...
Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Integrative Cancer Educator, Retired Pharmacist, Founder of Prevail Over Cancer and the Prevail Protocol.
If you’ve been diagnosed with cancer — or you’re supporting someone who has — you’ve probably heard about mushroom-based immune supplements. But not all mushroom extracts are created equal. AHCC (Active Hexose Correlated Compound) stands apart from the crowd, not because of marketing hype, but because of an unusually strong body of clinical research, including human trials published in peer-reviewed journals.
In this post, I’m going to walk you through exactly what AHCC is, where it comes from, how it differs from beta-glucan, what the laboratory and animal studies show, what human clinical studies have found, how it interacts with chemotherapy, rad...
Modified citrus pectin (MCP), Pectasol-C, is a form of pectin derived from the peel and pulp of citrus fruits. Unlike regular pectin—which is too large to be absorbed—MCP is processed into smaller, low‑molecular‑weight fragments that the body can absorb more easily.
MCP is rich in galactoside residues, which give it a unique ability to bind to certain proteins involved in cancer biology, especially galectin‑3.
Pectasol-C® is a brand of MCP.Â
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Much of MCP’s anticancer interest comes from its ability to bind and block galectin‑3, a protein involved in:
Galectin‑3 is overexpressed ...
Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, and Founder of Prevail Over Cancer™, and the Prevail Protocol™
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High-dose intravenous vitamin C (IVC) has reemerged as a promising adjunctive therapy in integrative oncology. Modern research highlights its unique pharmacology, potential anticancer mechanisms, and its ability to support patients undergoing chemotherapy, radiation, and immunotherapy. This guide breaks down the science, dosing considerations, safety labs, and clinical integration—supported by peer-reviewed medical literature.
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Oral vitamin C absorption is tightly limited by intestinal transporters, which cap blood levels even at high doses. In contrast, IV administration bypasses intestinal absorption and produces blood concentrations 100–500× higher than those required for a...