By Keith Bishop | Clinical Nutritionist, Cancer Coach, Retired Pharmacist | Prevail Over Cancer

If your liver has already done the hard work of neutralizing a toxin or excess hormone — but your gut is quietly undoing all of that work before it can leave your body — you have an enzyme problem.

That enzyme is called beta-glucuronidase. And one of the most-researched natural compounds for addressing it is calcium D-glucarate.

In this post, we'll break down exactly what calcium D-glucarate is, how it works at the biochemical level, what the research shows across multiple cancer types, and where it fits inside a comprehensive integrative oncology protocol.

What Is Calcium D-Glucarate?

Calcium D-glucarate is the calcium salt of D-glucaric acid — a naturally occurring compound produced in small amounts by the human body and found abundantly in a variety of plant foods. The calcium is there for stability in supplement form. The active ingredient is the glucarate portion.

Glucaric a...

The Evidence-Based Guide to Active Hexose Correlated Compound — How It Works, What Human Studies Show, and How to Use It Strategically With Cancer Treatment

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Integrative Cancer Educator, Retired Pharmacist, Founder of Prevail Over Cancer and the Prevail Protocol.

If you’ve been diagnosed with cancer — or you’re supporting someone who has — you’ve probably heard about mushroom-based immune supplements. But not all mushroom extracts are created equal. AHCC (Active Hexose Correlated Compound) stands apart from the crowd, not because of marketing hype, but because of an unusually strong body of clinical research, including human trials published in peer-reviewed journals.

In this post, I’m going to walk you through exactly what AHCC is, where it comes from, how it differs from beta-glucan, what the laboratory and animal studies show, what human clinical studies have found, how it interacts with chemotherapy, rad...

Understanding fungal DNA in cancer tumors, terrain imbalances, antifungal foods, and how metabolism shapes fungal behavior in the body.

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist, and Founder of Prevail Over Cancer and the Prevail Protocol. 

 Why Fungi Are Being Found in Human Tumors

Large sequencing studies have confirmed that low-abundance fungal DNA and fungal cells appear across multiple cancer types — including breast, lung, GI, melanoma, and gynecologic tumors. These findings do not indicate infection and do not establish fungi as carcinogens. Instead, they highlight fungi as ecological participants within the tumor microenvironment.

• The Cell pan‑cancer analysis identified cancer‑type-specific fungal signatures, often co-occurring with distinct bacterial communities and immune phenotypes.
• A second Cell study confirmed the presence of fungi in GI and lung tumors and demonstrated associations with immune infiltration...

Pizza’s dark side: burnt crust, processed meats, and blood sugar spikes can raise cancer risks—here’s what the science says.

Written by Keith Bishop, Integrative Cancer Educator, Clinical Nutritionist, Retired Pharmacist, and Founder of Prevail Over Cancer.

🔥Burnt Crust and Acrylamides: A Carcinogenic Combo?

When pizza crust is overcooked or charred, it can form acrylamides—chemical compounds linked to increased cancer risk. Acrylamides are especially prevalent in carbohydrate-rich foods cooked at high temperatures, such as baked goods and fried potatoes. Though research is ongoing, acrylamides are genotoxic (damage DNA) and carcinogenic in animal studies.

Additionally, the blackened edges of pizza crust may contain polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HCAs), both of which are formed during high-heat cooking and have been shown to damage DNA and promote cancer development.[i]

Learn more from the National Cancer Institute: Chemicals in Meat Cooked at ...